10 Popular Weight Loss Pills and Supplements Reviewed

There are many different weight loss solutions out of there.

This includes all forms of pills, drugs, and herbal supplements.

These are claimed to help you lose weight or make it less complicated to lose weight blended with different strategies.

They have a tendency to work through one or more of these mechanisms:

  1. Reduce appetite,  making you sense more full so that you eat fewer calories
  2. Reduce absorption of vitamins like fats, making you're taking in fewer calories
  3. Increase fat burning, making you burn greater energy

Here are the 10 most popular weight loss pills and supplements, reviewed by science.

1. Garcinia Cambogia Extract


Garcinia cambogia has become popular global after being featured at the Dr. Oz display in 2012.

It is a small, green fruit, fashioned like a pumpkin.

The skin of the fruit consists of hydroxycitric acid (HCA). This is the active element in Garcinia Cambogia extract, which is marketed as a food plan pill.

How it really works: Animal studies show that it may inhibit a fat-producing enzyme within the body and growth ranges of serotonin, doubtlessly supporting to reduce cravings.

Effectiveness: One look at 130 people as compared to garcinia in opposition to a dummy pill. There turned into no difference in weight or frame fats percentage among businesses.

A 2011 assessment that looked at 10 research on garcinia Cambogia found that, on average, it brought on a weight loss of about 2 kilos (0.88 kg) over numerous weeks.

Side effects: There are no reports of significant side effects, but a few reviews of slight digestive issues.


Even though Garcinia Cambogia may additionally motive modest weight loss, the effects are so small that they possibly won’t also be substantive.

Hydroxycut has been around for more than a decade and is presently one of the most famous weight reduction supplements within the world.

There are numerous different sorts, but the most commonplace one is honestly referred to as “Hydroxycut.”

How it works: It contains numerous ingredients that are claimed to assist with weight loss, which includes caffeine and a few plant extracts.

Effectiveness: One examination confirmed that it prompted 21 lbs (9.5 kg) of weight loss over a 3-month duration.

Side effects: If you're caffeine sensitive, you may revel in anxiety, jitteriness, tremors, nausea, diarrhea, and irritability.


Unfortunately, there may be the handiest one study on this supplement and no facts on lengthy-time period effectiveness. More studies are wanted.

Caffeine is the most typically fed psychoactive substance in the international.

It is discovered obviously in coffee, green tea, and darkish chocolate, and brought to many processed foods and beverages.

Caffeine is a well-known metabolism booster and is frequently delivered to industrial weight reduction supplements.

How it really works: Short-term research has shown that caffeine can enhance metabolism by using 3-11%, and growth fats burning by way of as much as 29%.

Effectiveness: Some research displays that caffeine can motive modest weight reduction in people.

Side effects: In a few human beings, high amounts of caffeine can motive anxiety, insomnia, jitteriness, irritability, nausea, diarrhea, and different symptoms. Caffeine is likewise addictive and might reduce the satisfaction of your sleep.

There honestly is no need to take a supplement or a tablet with caffeine in it. The excellent resources are first-class espresso and green tea, which also have antioxidants and different fitness benefits.


Caffeine can improve metabolism and beautify fats burning in the short term. However, a tolerance to the outcomes may additionally develop quickly.

Orlistat is a pharmaceutical drug, bought over-the-counter below the name Alli, and below prescription as Xenical.

How it works: This weight loss tablet works by means of inhibiting the breakdown of fats within the intestine, making you're taking in fewer calories from fats.

Effectiveness: According to a big review of 11 research, orlistat can grow weight loss by means of 6 kilos (2.7 kg) in comparison to a dummy pill.

Other benefits: Orlistat has been proven to lessen blood strain barely, and reduced the risk of growing type 2 diabetes by using 37% in a single examination.

Side effects: This drug has many digestive aspect outcomes, consisting of unfastened, oily stools, flatulence, common bowel actions which can be hard to manipulate, and others. It may also make a contribution to deficiency in fat-soluble nutrients, together with nutrients A, D, E, and K.

It is typically encouraged to observe a low-fat eating regimen whilst taking orlistat to minimize side outcomes.

Interestingly, a low-carb eating regimen (without drugs) is as powerful as both orlistat and a low-fat food regimen combined.


Orlistat, additionally referred to as Alli or Xenical can lessen the quantity of fat you soak up from the weight loss program and help you lose weight. It has many facet consequences, some of which are particularly ugly.

Raspberry ketone is a substance observed in raspberries, that's responsible for their wonderful smell.

A synthetic version of raspberry ketones is offered as a weight-loss complement.

How it really works: In remoted fat cells from rats, raspberry ketones grow the breakdown of fat and increase tiers of a hormone referred to as adiponectin, believed to be related to weight loss.

Effectiveness: There is not a single look at raspberry ketones in people, but one rat take a look at the use of massive doses showed that they reduced weight gain.

Side effects: They may also reason your burps to smell like raspberries.


There isn't any proof that raspberry ketones purpose weight loss in humans, and the rat research displaying it to work used massive doses.

Green coffee beans are in reality normal espresso beans that haven’t been roasted.

They incorporate materials believed to help with weight loss, caffeine, and chlorogenic acid.

How it really works: Caffeine can boom fats burning, and chlorogenic acid can sluggish the breakdown of carbohydrates within the gut.

Effectiveness: Several human research has shown that inexperienced coffee bean extract can help human beings lose weight.

An overview of 3 research observed that the complement made humans lose 5.4 more pounds (2.5 kg) than placebo, a dummy tablet.

Other benefits: Green coffee bean extract might also assist in lower blood sugar stages, and decrease blood stress. It is likewise high in antioxidants.

Side effects: It can reason the equal facet-consequences as caffeine. The chlorogenic acid in it can also purpose diarrhea, and some people can be allergic to inexperienced coffee beans.


Green coffee bean extract can also motive modest weight loss, however, remember that among the studies have been enterprise-subsidized.

Glucomannan is a sort of fiber located in the roots of the elephant yam, additionally known as konjac.

How it really works:  Glucomannan absorbs water and becomes gel-like. It “sits” in your gut and promotes a sense of fullness, helping you eat fewer calories.

Effectiveness: Three human studies confirmed that glucomannan, combined with a healthful weight loss plan, can help humans lose 8-10 pounds (3.6-4.5 kg) of weight in five weeks.

Other benefits: Glucomannan is a fiber that can feed the pleasant bacteria in the gut. It can also lower blood sugar, blood cholesterol, and triglycerides, and is very powerful against constipation.

Side effects: It can motive bloating, flatulence, and gentle stools, and can interfere with some oral medicines if taken at the identical time.

It is vital to take glucomannan about half of an hour before food, with a pitcher of water. If you would love to strive for it, Amazon has an excellent choice to be had.

BOTTOM LINE:Studies always display that the fiber glucomannan, while blended with a wholesome food regimen, can help human beings shed pounds. It also ends in improvements in numerous fitness markers.

Meratrim is a relative newcomer to the food regimen pill market.

It is a mixture of plant extracts that may trade the metabolism of fat cells.

How it really works:  It is claimed to make it more difficult for fat cells to multiply, lower the number of fats that they select up from the bloodstream, and help them burn stored fat.

Effectiveness: So some distance, the handiest one to take a look at has been achieved on Meratrim. A total of one hundred overweight human beings have been located on a strict 2000 calorie food regimen, with either Meratrim or a dummy pill.

After 8 weeks, the Meratrim organization had misplaced 11 kilos (5.2 kg) of weight and 4.7 inches (11.9 cm) off their waistlines. They also had improved best of lifestyles and decreased blood sugar, cholesterol, and triglycerides.

Side effects: No side effects have been reported.


One study confirmed that Meratrim brought on weight loss and had several other health advantages. However, the examination turned into enterprise-subsidized and extra studies are wanted.

Green tea extract is a popular element in many weight reduction dietary supplements.

This is because numerous studies have proven the principal antioxidant in it, EGCG, to useful resource for fat burning.

How it really works: Green tea extract is believed to increase the activity of norepinephrine, a hormone that facilitates you burn fat.

Effectiveness: Many human studies have proven that inexperienced tea extract can boom fat burning and cause fat loss, in particular inside the belly region.

Side effects: green tea extract is usually nicely tolerated. It does incorporate some caffeine and may motive signs and symptoms in folks who are caffeine sensitive.

Additionally, all the health blessings of drinking inexperienced tea must observe to green tea extract as nicely.

BOTTOM LINE:Green tea and inexperienced tea extract can increase fat burning barely and might help you lose belly fats.

10. Conjugated Linoleic Acid (CLA)

Conjugated linoleic acid, or CLA, has been a popular fat loss complement for years.

It is one of the “healthier” trans fats and is determined clearly in some fatty animal ingredients like cheese and butter...

How it really works: CLA may also reduce the urge for food, improve metabolism and stimulate the breakdown of body fat.

Effectiveness:  In a chief evaluation of 18 distinctive research, CLA prompted weight loss of approximately 0.2 kilos (0.1 kg) consistent with week, for up to 6 months.

According to every other evaluation have look at from 2012, CLA could make you lose about three lbs (1.3 kg) of weight, compared to a dummy tablet.

Side effects: CLA can motive numerous digestive side effects, and may have harmful results over the long term, potentially contributing to fatty liver, insulin resistance, and elevated infection.


CLA is an effective weight reduction complement, but it may have dangerous effects over the long term. The small quantity of weight reduction isn't always worth the threat.

Additionally, many prescription weight reduction drugs were proven to be effective.

The maximum common ones are Contrave, Phentermine, and Qsymia.

According to a recent 2014 evaluation study, even prescription weight reduction tablets don’t paintings in addition to what you'll desire.

On common, they'll assist you to lose up to three-9% of body weight as compared to a dummy pill.

Keep in thoughts that this is simplest whilst mixed with a wholesome weight-loss food regimen. They are ineffective on their personal, and infrequently an approach to weight problems.

Not to say their many facet effects.

WITHDRAWAL OF BELVIQIn February 2020, the Food and Drug Administration (FDA) asked that the weight reduction drug lorcaserin (Belviq) be eliminated from the U.S. Market. This is due to an accelerated wide variety of most cancer cases in those who took Belviq compared to placebo. If you’re prescribed or taking Belviq, stop taking the drug and talk together with your healthcare provider about alternative weight management techniques.

Out of the 12, these are the clear winners, with the most powerful proof to lower back them up:

  • Weight loss: Glucomannan, CLA, and Orlistat (Alli)
  • Increased fat burning: Caffeine and green tea extract

However, I need to suggest towards Orlistat due to the unsightly facet consequences, and against CLA due to the damaging outcomes on metabolic health.

That leaves us with glucomannan, green tea extract, and caffeine.

These supplements can be useful, however, the outcomes are modest at a first-rate.

Unfortunately, NO complement or tablet absolutely works that properly for weight loss.

They may additionally supply your metabolism a bit of a nudge and assist you to lose some kilos, however that’s in which it ends, lamentably.

Cutting carbs and eating more protein are nevertheless the best approaches to shed pounds, and paintings better than all the weight loss program capsules blended.